CRO Services

When protein complexity becomes a bottleneck, our engineered ExpreS2 platform delivers.
Fast timelines, high yields, and native-like folding & glycosylation.

ExpreS2ion has successfully developed and produced
over 500 different hard-to-express proteins
with a success rate above 90 percent.

Challenges We Solve

How We Help

Why Trust Us

  • Difficulty expressing complex, disulfide-rich, or heavily glycosylated proteins

  • Low or inconsistent yields from CHO, HEK, or E. coli systems

  • Misfolding or instability resulting in inactive proteins

  • Long timelines and delays in early-stage development

  • Batch variability in research-grade protein supply

  • Need for a virus-free, scalable expression system suitable for clinical transition and/or production

  • ExpreS2™ Platform: High success rate with >500 proteins expressed

  • Native-like Protein Quality: Proper folding and eukaryotic glycosylation

  • No Baculovirus Required: Simplifies workflows and reduces regulatory hurdles

  • Scalable Production: From mg-scale feasibility to g-scale preclinical batches

  • Rapid Timelines: Feasibility studies completed in weeks

  • GlycoX-S2™: Glyco-engineered variants available for enhanced immunogenicity or function

  • Flexible Engagement: Fee-for-service, project-based campaigns, and licensing options

  • Clinically Validated Platform: Used in 10+ clinical-stage programs, incl. a full regulatory approval in a finalized phase 3.

  • Proven Track Record: 15+ years of experience and >90% expression success

  • Approved Product: ExpreS2™-produced antigen received full regulatory approval post-Phase III

  • Trusted by Industry Leaders: Collaborations across pharma, biotech, and diagnostics

  • Smooth Tech Transfer: Proven handover to GMP CDMOs

  • Scientifically Grounded: Built on academic expertise, validated by peer-reviewed research

If you want to know more, please contact: info@expres2ionbio.com or +45 2222 1019