Proof of concept in animals for a new potential breakthrough malaria vaccine
An effective vaccine is a priority for malaria control and elimination. The leading candidate in the Plasmodium falciparum blood stage […]
Structure of Plasmodium falciparum Rh5–CyRPA–Ripr invasion complex
Plasmodium falciparum causes the severe form of malaria that has high levels of mortality in humans. Blood-stage merozoites of P. falciparuminvade erythrocytes, […]
Structural basis for recognition of the malaria vaccine candidate Pfs48/45 by a transmission blocking antibody
The quest to develop an effective malaria vaccine remains a major priority in the fight against global infectious disease. An […]
Production, quality control, stability, and potency of cGMP-produced Plasmodium falciparum RH5.1 protein vaccine expressed in Drosophila S2 cells
Plasmodium falciparum reticulocyte-binding protein homolog 5 (PfRH5) is a leading asexual blood-stage vaccine candidate for malaria. In preparation for clinical […]
Human vaccination against Plasmodium vivax Duffy-binding protein induces strain-transcending antibodies
The ExpreS2 system was used for the production of recombinant PvDBP_RII (SalI) protein for ELISA-based assays in the article “Human […]
“Accelerating the clinical development of protein-based vaccines for malaria by efficient purification using a four amino acid C-terminal ‘C-tag’”
The ExpreS2 system was used in the production of the recombinant protein produced in the study “Accelerating the clinical development of […]
The ExpreS2 system used in a new study published in Vaccine “Comparison of functional assays used in the clinical development of a placental malaria vaccine”
The article “Comparison of functional assays used in the clinical development of a placental malaria vaccine” was recently published in […]
The ExpreS2 system is used for production of full-length soluble Plasmodium falciparum RH5 protein vaccine
The article “Production of full-length soluble Plasmodium falciparum RH5 protein vaccine using a Drosophila melanogaster Schneider 2 stable cell line […]
ExpreS2ion Biotechnologies contributes to scientific article
ExpreS2ion Biotechnologies’ scientists contributed to the research for the article by Thrane et al, ”Bacterial superglue enables easy development of […]
Human Endothelial Protein C receptor (EPCR) expressed with the ExpreS2 system.
Structural Conservation Despite Huge Sequence Diversity Allows EPCR Binding by the PfEMP1 Family Implicated in Severe Childhood Malaria C.K.Y Lau, […]